Mathew’s eldest son, John was born on the 15th September 1940. He passed M.Sc. from the University of Baroda, with rank. He obtained a Ph.D from the same university. He worked in the research wing of Hindustan Liver in Mumbai for some period. Later he worked as a scientist in Canada and the United States of America. He has also worked as a scientist at Johnson & Johnson in New Jersey. Many research papers of him, have been published. He married Kottayam Kanjikuzhy Valayil, Philip’s daughter Mary (Kukku). Mary also works as a scientist. They live in America. They have a son named Justin and a daughter named Sheryl. Sheryl holds a master’s degree in medicine and practices as a pediatrician in New Jersey.